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Date: 01.05.2015
From: Katie

Subject: Factors

Hi does anyone know anything about ra factors please?
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Date: 02.05.2015
From: Merry

Subject: Re: Factors

Hello Katie. Do you mean RA factors, as in sero negative or positive , or just RA levels (factors) in general ?
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Date: 02.05.2015
From: Colin W

Subject: Re: Factors

hi Katie , about 80% of people with RA are sero positive , to be positive your levels of rheumatoid factor are above 20 IU/mL but alot of people that are sero negitive do develop positive FR over time

most the people that develop severe RA tend to have very high RF , mine was 450 when they tested it 19 years ago , they have never checked it again

having positive RF dont mean you have RA , check on wiki
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Date: 02.05.2015
From: Katie

Subject: Re: Factors

I've been told my ra factor is 20.9. I have fluid in both knees and are very painful and1 wrist. My mum has had ra since she was mid 30's her mum and nan too. I'm 29. Will it just get worse?
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Date: 02.05.2015
From: Colin W

Subject: Re: Factors

Katie , think you need a steriod injection into both knees , I had this when I first developed RA , they done my ankles at the same time , after 24 hours total bedrest my knees felt good but my ankles were both hot

are you under a rheumatoligist , 20.9 is pretty boarderline but with the problems you are having they need to confirm what is going on
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Date: 02.05.2015
From: Katie

Subject: Re: Factors

Hi Colin thanks for replying. They seem to have given me the results and left me too it. I've got a phone consultation with my doctor on 11 th May but until them been told to take ibuprofen!! I've got two young children one of which is so hyperactive not sure how much much longer I can run after her for
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Date: 03.05.2015
From: Merry

Subject: Re: Factors

Hi Katie I hope all goes well for you. Colin, do different hospitals have different levels of RA factors ? On my notes it says I am sero negative as under a baseline of 30 ?
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Date: 04.05.2015
From: Colin W

Subject: Re: Factors

hi , cant realy help you with your question , just not qualified , I would ask your GP/Consultant , there are other test they can do like Anticitrullinated protein antibodies (ACPAs) are autoantibodies (antibodies directed against an individualās own proteins) that are directed against peptides and proteins that are citrullinated. They are present in the majority of patients with rheumatoid arthritis.

the main difference being sero negative is normaly RA is easier to control & they dont normaly let you have the newer biologics rituximab/tocilizumab & abatacept, but this may change soon
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Date: 05.05.2015
From: Merry

Subject: Re: Factors

Thanks Colin , I haven't had citrullinated wotsits name test done, I don't know why its never been requested ? Would that be positive if I was RA negative ?
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