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Date: 02.02.2009
From: Richard

Subject: Researching the possible causes and mechanisms of Rheumatoid Arthritis

I suffer from Rheumatoid Arthritis, it strikes me that there are plenty of suffers who have the experience, intelligence and insight to investigate this condition.
Such an investigation would require common sense, coordination, discernment and organisation.

Has anybody got the time and inclination?

Richard
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Date: 02.02.2009
From: Richard

Subject: Re: Researching the possible causes and mechanisms of Rheumatoid Arthritis

INVESTIGATION INTO THE HUMAN IMMUNE SYSTEM - DOC1

FOREWORD

Scientific literature often contains assertions that have not been sufficiently confirmed.
I am not sure to what extent this happens in biological literature.
It appears prudent to be wary.
I am aware that a recent accepted perception of the immune system has changed.

Information that appears incoherent with other allegedly coherent information should if possible be the cause of further investigation.

I am conducting an investigation
therefore it may be appropriate for me to consider some of the information obtained for the purpose to be unsubstantiated,
until or unless further information is obtained to confirm it.

The following information should be considered unsubstantiated unless it agrees with common sense experience or coherent information confirms it.

When I refer to a body system, I am referring to one that is working well unless I state otherwise.

Richard
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Date: 02.02.2009
From: Richard

Subject: Re: Researching the possible causes and mechanisms of Rheumatoid Arthritis

I am at present researching the development of blood cells.


Richard
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Date: 02.02.2009
From: Richard

Subject: Re: Researching the possible causes and mechanisms of Rheumatoid Arthritis

THE HUMAN IMMUNE SYSTEM is the native internal system for protection from unwanted foreign matter and organisms and native damaged and dysfunctional matter and organelles (pejoratively called antigens).
The immune system perceives detected antigens as potentially hazardous to well function of the body.
The immune system battles and usually eliminates the potential hazard from antigens it is able to detect.

red bone marrow is the individualās source of blood and lymph cells.
The blood and lymphatic networks are channels used to deploy the blood and lymph cells

Richard
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Date: 02.02.2009
From: richdub@talktalk.net

Subject: Re: Researching the possible causes and mechanisms of Rheumatoid Arthritis

For the most part, blood cells and platelets develop from a common precursor cell in the red bone marrow.

The precursor cell, because it gives rise to many different cell types yet still remains to make more, is also called a stem cell.

The term "stem cell" is generic, and could refer not only to a cell type that manufactures blood cells but also to cells that generate the mature cells of other tissues

The particular stem cell that produces our blood cells is the hemocytoblast.
"Hemo-" is for blood, "cyto" is for cell, and "-blast" means a cell that can divide to make more cells.
Taken together, a hemocytoblast is a cell that can divide to make more and more blood cells.
The hemocytoblast remains in the red bone marrow.

There are two types of bone marrow: red marrow and yellow marrow.
hemocytoblasts also make the red blood cell, which gives marrow it is in is a red appearance.

A hemocytoblast can divide many times.
Each time it divides (mitosis) it is into two, one of its two daughter cells remains as a hemocytoblast; this ensures the continued existence of hemocytoblasts in the bone marrow.
The other daughter cell will change into a different type of cell.
The type of cell it becomes depends on the signals (like hormones) that find their way to the bone marrow from the blood.

Explanations: HEMOCYTOBLAST (Also called hemoblast, lymphoidocyte)
A pluripotential blast or stem cell thought to be capable of giving rise to all other blood cells.

Explanations: BLAST CELL: A cell that can divide to make more cells.

Richard
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