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Date: 18.04.2010
From: connor

Subject: Methotrexate & Headaches.

Hello All,

Have been on mtx for about 7 months now. 15mg dose. My problem is Psoriatic Arthritis and Pustular Psoriasis.

I was told to take it on a Monday night, but was finding that the following morning I was waking up with a real humdinger of a headache which lasted most of the day and even into Wednesday.

As an experiment I tried taking it on Monday morning instead and I've found that whilst a headache still develops about mid afternoon it is nowhere near as bad.

Thats been the case for 3 weeks now. I thought I would pass my finding on in case it suits
any of you.

Regards to all..Connor.
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Date: 18.04.2010
From: Jill

Subject: Re: Methotrexate & Headaches.

Hi Connor....interesting, gald that works for u, all info and support is most welcome, so thanks for that.....I take mine at night and after three years of taking it now, I now dont tend to suffer the side affects re the headaches and the sicky feeling as much, body must have gotten use to it, after all this time....tc Jill
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Date: 19.04.2010
From: Lynn B

Subject: Re: Methotrexate & Headaches.

Hi connor have been on mtx for five months now, and i cant get rid of the headache have it constantly, the cold sores and mouth ulcers on 17.5mg rheumy nurse doesnt think its working so so i am going on 2 or 3 other meds as well as mtx. Every few days i have new parts joining the party, just waiting to see rheumy on the 25th may. I am glad you seem to be coping ok with it. tc Lynn.
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Date: 19.04.2010
From: jill

Subject: Re: Methotrexate & Headaches.

Hi Lynn I get terrible cold sores, but i use to get them in child hood too....glad i dont get mouth sores, they r nasty, but i do get absesses, soon I wont have any teef!!! lol then no more absesses heheha......heads r so much better, think it does take a while to get that part sorted out, beeen on mine 3 years now, and my syptoms have begun to get less from the rotten side affects!....we r all diff, so anyone starting MTX, pls dont worry,. some r better on it than others, depends if ya stomach is strong I guess.....x
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Date: 20.04.2010
From: shaz

Subject: Re: Methotrexate & Headaches.

hi all been on injectable mtx for last 4 months now 22.5mg couldnt cope with the pills was always sick the headaches havent improved at all 14 months on still wake up morning after mtx with a banging head even when i was learning how to inject mtx and having to do it on a morning i always ended up with headache and found that the side effects was worse i would much rather sleep through the side effects,now the rheumy is talking about adding sulphasalazine and from what i have read about this it no better then mtx for the side effects so looks like my poor stomach in for another rollercoaster ride
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