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Date: 27.05.2009
From: Sandy

Subject: Any suggestions as to why the MTX is making me feel really sick now?

Hi, I'm taking 20mg of MTX alongside Humira and over the past few weeks I've found the MTX is making me feel dreadful - really nauseous (like right now). I've been on mTX for years now and have always tolerated it well. Doc put my dose down from 25mg to 20mg in November because it was making me feel ill and now it's happening again. Any thoughts?! I already split the does am/pm. It's really hard as my 3 yr olds would like to play and I want to lie down!
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Date: 27.05.2009
From: Jill

Subject: Re: Any suggestions as to why the MTX is making me feel really sick now?

Hi sandy

Jill here, Ive been on Methrexate 17.5 for three eyars, along with Enbrel just over a year injections, Ive sked in the past if I could go higher up on the Methrexate, my Rhumatologist said NO WAY, too high a dose as it is.... seems your dose is far higher than mine, just wondering becos I feel sick the day i take my MTX, Im suere Id feel sick on that amount...Dont know y u r suddenly feeling sick on it tho, mb its your bodys ways of saying to either Slow down(try get littlun to rest with u, easier said than done I know) or your dose is too high for u at this moment ?

Let us know how u get on

Jill x
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Date: 27.05.2009
From: Sandy

Subject: Re: Any suggestions as to why the MTX is making me feel really sick now?

Yes, I was on 25mg for ages - years - to keep my RA under control as much as possible and then about 18 months ago I finally got the anti-TNF approved. Rheumy was really NOT keen to reduce it to 20mg at the end of last yr (and he was prob right as I ache and feel a bit 'doughy' around my finger and shoulder joints...). I guess I will have to ask GAH!its all such a faff isnt it. thanks
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