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Date: 07.04.2014
From: Julie

Subject: Mtx injections v tablets

Has anyone been on the tablets, then gone onto injections and then reverted back to tablets

I did this about six weeks ago, (after few months I couldn't cope with injecting myself), I have found that the last 3 weeks I have felt as if I am back at the beginning again, lot of pain and feel totally down and thoroughly miserable.

Have I caused this myself I wonder? Luckily I am at rheumy tomorrow but would still like to know if anyone else experienced 'going backwards'

Does everyone have a DAS28 score, Ive never been told mine.
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Date: 07.04.2014
From: Colin W

Subject: Re: Mtx injections v tablets

hi Julie , got the T-shirt for the injections lol , just could not do it & went back on tablets , later this year they will change it to pen injections which is so much easier , just press a button

you can work your das28 score out , it needs to be over 5 to get onto biologics , http://www.das-score.nl/das28/DAScalculators/dasculators.html
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Date: 08.04.2014
From: Julie

Subject: Re: Mtx injections v tablets

Hi Colin, hope your well, I am going to ask about the pens this afternoon, I think I could cope with that!!

Thannks for info re das28 score I will have a look.

Are you still on mtx tablets plus your biologic? Do you have to inject a biologic, I have read about them but they all (apart from infusions) look as if they are injections - hopefully by pen.
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Date: 08.04.2014
From: Linda Bradley

Subject: Re: Mtx injections v tablets

Hi Julie, I was on mtx tablets for 9 months last year. Made me feel ill. Headache's and sick. So in dec I went on metaject. Still felt ill. Flu like for 3days. Last week I saw rhuemy nurse and she said to stop it, gonna go on sulfasalazine. now. But have to wait till appt and prescription! Hope you get sorted
Linda
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Date: 08.04.2014
From: Eve

Subject: Re: Mtx injections v tablets

I went from tablets to injections then was taken on and off due to issues (not just the mtx, infections and such).

I'm back on tablets now though only on 10mg per week to get on a stable dose with a view to going on a biologic (appointment on Thursday!!!).

I've just had shingles so have been off the mtx again...argh...my immune system hates me! Had bloods yesterday and hoping to get back on it later this week.

May be another spanner in the works with the biologics as have to see another consultant (not rhumo) first but we shall see.

It's been very much on and off meds for me for years. I am very prone to infections and such.
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Date: 09.04.2014
From: Julie

Subject: Re: Mtx injections v tablets

thanks everyone, I had appointment yesterday but not with my normal consultant, but saying that she was just as thorough. She didn't think eating the oranges or changing back to tablets had anything to do with me still being in pain.

To be honest with you I didn't feel in that much pain, she pressed my fingers and said does it hurt, I said no, they are only stiff first thing, but then she said 'I know you say they don't hurt but I know that they are really inflamed and its the steroids that are masking your pain'

I am in process of reducing steroids so I thought that might have been problem, but nothing was said about that. Couple of weeks ago my crp was 25 but last week it had gone up again to 45.

Anyway she is going to have a word with the head rheumatologist to see about biologics, but I have to wait 4 weeks. Might see if I can get any pre tests done before then, tb etc., will have to have a word with g.p.
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Date: 11.04.2014
From: Mgt

Subject: Re: Mtx injections v tablets

Colin. any idea when we can get the pens?
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Date: 11.04.2014
From: Colin W

Subject: Re: Mtx injections v tablets

Hi , was told later this summer , they are out but not sure when we will be allowed to have them , looks like the Metoject PEN will be from 7.5mg to 30mg

http://www.drugs.com/uk/metoject-pen-15-mg-solution-for-injection-in-pre-filled-pen-leaflet.html

Julie , its about time they gave you one of the biologics , CRP of 25 is very high let along 45 , anyway starting my new biologic today so hope it goes well with the infusion & they are changing them to PENs later this year
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Date: 11.04.2014
From: Julie

Subject: Re: Mtx injections v tablets

Colin hope it goes okay with your infusion, let us know how it went.

agree I think I have waited too long for biologics, couple of months ago my crp was 220!! I thought that 25 was good:(

Just have to keep as I am for next 4 weeks.
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Date: 11.04.2014
From: Mgt

Subject: Re: Mtx injections v tablets

Ta Colin- yeah just asked my rheumy nurse and she says in summer but no date yet
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