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Date: 03.12.2010
From: davina

Subject: medication increase and more.

Hi hope every1 is ok and not having to many problems with this weather.
not been on for a while as i've had my Hernia operation 3 weeks ago and been recovering.
since then my knees as been so painful that i have started using crutches for going out due to my knees giving way.
i went to see my rheumy nurse last week who was surprised with my ultra scan which showed 3 fluid sacs on my right knee and 2 on my left knee. so she arranged a mri which is in 2 week. so we will see.
my crp and all other markers are very high so she decided to up the methotrexate to 25 mg and put my on to plaquenil 400 mg daily.
i am also on prednisolone 15mg, diclofenac, and pain killer as needed.

has any1 else been on this combo of meds and how did it affect you.
i'm a little worried about such a high dose of methotrexate and yet another med. i feel like i'm going to be rattling soon. lol

sorry to rattle on hope someone will understand. thanks davina. x
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Date: 06.12.2010
From: Shirley

Subject: Re: medication increase and more.

Hi Davina, I don't have any answers I'm afraid but I can sympathise as I'm feeling the same. Mtx 25mg, diclofenac, Tramadol and I've got to take 400mg Plaquenil. I haven't started it yet as I've been feeling quite good after a couple of steroid injections in my shoulders and like you say, scared I'm gonna be rattling soon! Hopefully someone else can share their experience of these? Good luck. x
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Date: 06.12.2010
From: dolly

Subject: Re: medication increase and more.

hi davina. my name is dolly. i've had RA for 41 years. i've had 30 surgeries. i've been on many RA meds and it looks like you're on a good "cocktail". don't worry your rheumy will find a good "cocktail" that will work for you. right now my "cocktail" is humira, prednisone, and hydromorphone [painkiller]. i'm doing "o.k." considering how bad i used to be. i've had a successful knee replacement, a very big difference. you take care now. talk soon. dolly
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Date: 06.12.2010
From: Caroline

Subject: Re: medication increase and more.

Hello Davina -and Shirley!
I'm also on 25mg. of methotrexate (amongst other things such as Enbrel and Naproxen). Recently I mentioned to my consultant nurse that my hair seems to be thinning and falling out possibly because of my 'high dose' of methotrexate. Although the hair loss is quite likely caused by the methotrexate, she pointed out that 25mg. is a low dose compared to the amounts given to treat cancer, for example.
Good luck with your combination of drugs. RA seems to need an ever changing mix of different medicines until the right formula is found and that solution may last for a short time before having to be reviewed!
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Date: 06.12.2010
From: davina

Subject: Re: medication increase and more.

hello and thank you all for replying.
shirley i am so glas someone else understands what i'm going tho at the same time its a bit comforting knowing there are so many nice people on this site that cares too.
to Dolly you sound like a strong woman having so many operations, i hope you are not needing anymore to soon.
Caroline i hope your hair propblem will sort it self out maybe when you start decreasing your mtx?

thanks for replying everyone.xx
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Date: 07.12.2010
From: dolly

Subject: Re: medication increase and more.

davina, i'm good so far. my last surgery was getting a nodual from my foot in 07. i'm also i won't need any for awhile, but i must say, they all helped very successfully. i've also have had 2 heartattacks, i collapsed lung, and a kidney infection that got into my blood stream, so the docs handle me with "kid gloves" now. thanks for the reply. take care now, dolly.
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